A Rare Initial Presentation of Primary Diffuse Leptomeningeal PNET in a 10-Year-Old-Male.

Authors

• Peter Paul Lim
• Jagadeesh Ramdas
• Michal Ann Miller
• Conrad Schuerch
• George Wu

Publication/Presentation Date

12-1-2017

Abstract

Primary leptomeningeal primitive neuroectodermal tumors (PNETs) are extremely rare childhood central nervous system malignancies harboring a very poor prognosis. There is no consensus treatment for these tumors to date. We report a case of a 10-year-old male who presented with mental status change, hydrocephalus, intracranial and spinal diffuse leptomeningeal enhancement without a primary mass upon cranial imaging and a negative initial biopsy until five months into his presentation. He responded significantly well to initial chemotherapy and radiotherapy.

Volume

70

Issue

12

First Page

543

Last Page

545

ISSN

0038-3317

Published In/Presented At

Lim, P. P., Ramdas, J., Miller, M. A., Schuerch, C., & Wu, G. (2017). A Rare Initial Presentation of Primary Diffuse Leptomeningeal PNET in a 10-Year-Old-Male. South Dakota medicine : the journal of the South Dakota State Medical Association, 70(12), 543–545.

Disciplines

Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology

PubMedID

29334442

Department(s)

Department of Radiology and Diagnostic Medical Imaging

Document Type

Article