Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial.
Publication/Presentation Date
5-1-2018
Abstract
BACKGROUND: Tandem occlusions of the extracranial carotid and intracranial carotid or middle cerebral artery have a particularly poor prognosis without treatment. Several management strategies have been used with no clear consensus recommendations. We examined subjects with tandem occlusions enrolled in the ESCAPE trial and their outcomes.
METHODS: Data are from the ESCAPE trial. Additional data were sought on interventions for each subject.
RESULTS: There were 54 (17%) subjects with tandem extracranial and intracranial occlusions. Patients in the endovascular treatment arm (n=30) were more likely to be younger (median age 66 years, p
CONCLUSIONS: Tandem occlusions occurred in one-sixth of patients and were treated highly variably within the ESCAPE trial. While outcomes were similar, the best method to treat the carotid artery in patients with tandem occlusion awaits further randomized data.
TRIAL REGISTRATION NUMBER: NCT01778335.
Volume
10
Issue
5
First Page
429
Last Page
433
ISSN
1759-8486
Published In/Presented At
Assis, Z., Menon, B. K., Goyal, M., Demchuk, A. M., Shankar, J., Rempel, J. L., Roy, D., Poppe, A. Y., Yang, V., Lum, C., Dowlatshahi, D., Thornton, J., Choe, H., Burns, P. A., Frei, D. F., Baxter, B. W., Hill, M. D., & ESCAPE Trialists (2018). Acute ischemic stroke with tandem lesions: technical endovascular management and clinical outcomes from the ESCAPE trial. Journal of neurointerventional surgery, 10(5), 429–433. https://doi.org/10.1136/neurintsurg-2017-013316
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
29021311
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article