Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods.
Publication/Presentation Date
8-1-2017
Abstract
Rationale Efficacy of mechanical thrombectomy for acute stroke due to large vessel occlusion initiated beyond 6 h of time last seen well has not been demonstrated in randomized trials. Aim To establish whether subjects considered to have substantial areas of salvageable brain based on age-adjusted clinical core mismatch who can undergo endovascular treatment within 6-24 h from time last seen well (TLSW) have better outcomes at three months compared to subjects treated with standard medical therapy alone. Age-adjusted clinical core mismatch is defined by age (≤80 or >80 years), baseline National Institutes of Health Stroke Scale (NIHSS) (10-20 or ≥21), and core size (0-20 cm
Volume
12
Issue
6
First Page
641
Last Page
652
ISSN
1747-4949
Published In/Presented At
Jovin, T. G., Saver, J. L., Ribo, M., Pereira, V., Furlan, A., Bonafe, A., Baxter, B., Gupta, R., Lopes, D., Jansen, O., Smith, W., Gress, D., Hetts, S., Lewis, R. J., Shields, R., Berry, S. M., Graves, T. L., Malisch, T., Rai, A., Sheth, K. N., … Nogueira, R. G. (2017). Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods. International journal of stroke : official journal of the International Stroke Society, 12(6), 641–652. https://doi.org/10.1177/1747493017710341
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
28569123
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article