The majority of ruptured aneurysms are small with low rupture risk scores.
Publication/Presentation Date
9-1-2022
Abstract
BACKGROUND: Understanding the rupture risk of unruptured intracranial aneurysms has important clinical implications given the morbidity and mortality associated with subarachnoid hemorrhage (SAH). The ISUIA, UCAS, and PHASES studies provide rupture risk calculations.
OBJECTIVE: We apply the risk calculations to a series ruptured intracranial aneurysms to assess the rupture risk for each aneurysm (had they been discovered in the unruptured state).
METHODS: This is a retrospective study of 246 patients with SAH from a ruptured saccular aneurysm. The ISUIA, UCAS, and PHASES calculators were applied to each patient/aneurysm to demonstrate a theoretical annual risk of rupture dichotomized by aneurysm location.
RESULTS: The average diameter of the aneurysms was 5.5 ± 3.1 mm. Three quarters (75%) of the aneurysms measured48.8% were(Acomm) was the most common location of rupture (24.7%). Posterior communicating artery aneurysms (Pcomm) were the third most common at 16.2%. The average ISUIA 1-year rupture risk was 0.46 ± 0.008%. The average UCAS 1-year rupture risk was 0.93% ± 0.01. The annualPHASESrupture risk was0.32 ± 0.004%. The highest risk locations were the vertebral artery (up to 10.3% per year) and superior cerebellar artery (up to 2.7% per year). On average, Acomm aneurysms had 1 year risk no higher than 1.1% and Pcomm aneurysms no higher than 1.2% per year.
CONCLUSION: We observed that in a small retrospective series of ruptured aneurysms, the majority wereaneurysms, had they been discovered in the unruptured state, is low (
Volume
103
First Page
148
Last Page
152
ISSN
1532-2653
Published In/Presented At
Webb, M., Fischer, V., Farrell, R., Towne, J., Birnbaum, L., Rodriguez, P., & Mascitelli, J. (2022). The majority of ruptured aneurysms are small with low rupture risk scores. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 103, 148–152. https://doi.org/10.1016/j.jocn.2022.06.015
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
35878541
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article