The spectrum of neuroimaging abnormalities in solvent abuse and their clinical correlation.
Publication/Presentation Date
7-1-1996
Abstract
The brain magnetic resonance (MR) images and medical records of 6 patients with a history of chronic toluene abuse were reviewed retrospectively. The imaging findings were correlated with clinical impairment. The major findings consisted of atrophy (6 patients), white matter T2 hyperintensity (6 patients), and T2 hypointensity involving the basal ganglia and thalami (5 patients). Also seen was focal enhancement, previously unreported for patients who abused toluene. This study showed a correlation between the degree of neurological impairment and extent of white matter disease. There was no correlation between the severity of white matter changes on MR images and the presence of T2 hypointensity or duration of toluene abuse. There was no definite clinical evidence of damage to the basal ganglia and thalami despite the MR imaging finding of T2 hypointensity. Temporal evidence against the theory that toluene accumulation causes the T2 hypointensity was found.
Volume
6
Issue
3
First Page
167
Last Page
173
ISSN
1051-2284
Published In/Presented At
Caldemeyer, K. S., Armstrong, S. W., George, K. K., Moran, C. C., & Pascuzzi, R. M. (1996). The spectrum of neuroimaging abnormalities in solvent abuse and their clinical correlation. Journal of neuroimaging : official journal of the American Society of Neuroimaging, 6(3), 167–173. https://doi.org/10.1111/jon199663167
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
8704292
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article