Immune response of prostatic cancer patients to cytomegalovirus-infected and -transformed human cells.
Publication/Presentation Date
10-1-1978
Abstract
The indirect immunofluorescent test was used to determine the prevalence of humoral immunity to cytomegalovirus (CMV)-induced antigens in prostatic cancer patients as compared to age-matched controls. Significantly more prostatic cancer patients demonstrated high CMV-antibody titers than did the benign prostatic hyperplasia and nonurogenital cancer groups; however, no significant difference in reactivity was found between paients with prostatic cancer and transitional cell carcinoma of the urinary bladder. When screened against CMV-transformed human cell lines, the reactivity of the sera followed the rate of expression of CMV-related antigens of cell lines used in these tests.
Volume
42
Issue
4
First Page
1766
Last Page
1771
ISSN
0008-543X
Published In/Presented At
Laychock, A. M., Geder, L., Sanford, E. J., & Rapp, F. (1978). Immune response of prostatic cancer patients to cytomegalovirus-infected and -transformed human cells. Cancer, 42(4), 1766–1771. https://doi.org/10.1002/1097-0142(197810)42:4<1766::aid-cncr2820420415>3.0.co;2-o
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
81717
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article