Cell adhesion molecules: signalling functions at the synapse.
Publication/Presentation Date
3-1-2007
Abstract
Many cell adhesion molecules are localized at synaptic sites in neuronal axons and dendrites. These molecules bridge pre- and postsynaptic specializations but do far more than simply provide a mechanical link between cells. In this review, we will discuss the roles these proteins have during development and at mature synapses. Synaptic adhesion proteins participate in the formation, maturation, function and plasticity of synaptic connections. Together with conventional synaptic transmission mechanisms, these molecules are an important element in the trans-cellular communication mediated by synapses.
Volume
8
Issue
3
First Page
206
Last Page
220
ISSN
1471-003X
Published In/Presented At
Dalva, M. B., McClelland, A. C., & Kayser, M. S. (2007). Cell adhesion molecules: signalling functions at the synapse. Nature reviews. Neuroscience, 8(3), 206–220. https://doi.org/10.1038/nrn2075
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
17299456
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article