Validation of a DIXON-based fat quantification technique for the measurement of visceral fat using a CT-based reference standard.
Publication/Presentation Date
1-1-2019
Abstract
PURPOSE: The purpose of the study is to determine whether a novel semi-automated DIXON-based fat quantification algorithm can reliably quantify visceral fat using a CT-based reference standard.
METHODS: This was an IRB-approved retrospective cohort study of 27 subjects who underwent abdominopelvic CT within 7 days of proton density fat fraction (PDFF) mapping on a 1.5T MRI. Cross-sectional visceral fat area per slice (cm
RESULTS: Visceral fat area per slice ranged from 9.2 to 429.8 cm
CONCLUSION: MR- and CT-based visceral fat quantification are highly correlated and have good cross-modality reliability, indicating that visceral fat quantification by either method can yield a stable and reliable biomarker.
Volume
44
Issue
1
First Page
346
Last Page
354
ISSN
2366-0058
Published In/Presented At
Heckman, K. M., Otemuyiwa, B., Chenevert, T. L., Malyarenko, D., Derstine, B. A., Wang, S. C., & Davenport, M. S. (2019). Validation of a DIXON-based fat quantification technique for the measurement of visceral fat using a CT-based reference standard. Abdominal radiology (New York), 44(1), 346–354. https://doi.org/10.1007/s00261-018-1678-x
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
29946923
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article