Imaging of musculoskeletal manifestations in sickle cell disease patients.
Publication/Presentation Date
5-1-2017
Abstract
Sickle cell disease (SCD) is a hereditary red cell disorder with clinical manifestations secondary to sickling or crescent-shaped distortion of the red blood cells. Major clinical manifestations of SCD include haemolytic anaemia and vaso-occlusive phenomena resulting in ischaemic tissue injury and organ damage. Chronic sequelae of the anaemia and vaso-occlusive processes involving the musculoskeletal system include complications related to extramedullary haematopoiesis, osteonecrosis, myonecrosis and osteomyelitis. Sickle cell bone disease is one of the commonest clinical presentations. Awareness and knowledge of the imaging features related to these complications are essential for early diagnosis and prompt management. In this article, the pathophysiology and key imaging findings related to these complications are reviewed.
Volume
90
Issue
1073
First Page
20160130
Last Page
20160130
ISSN
1748-880X
Published In/Presented At
Kosaraju, V., Harwani, A., Partovi, S., Bhojwani, N., Garg, V., Ayyappan, S., Kosmas, C., & Robbin, M. (2017). Imaging of musculoskeletal manifestations in sickle cell disease patients. The British journal of radiology, 90(1073), 20160130. https://doi.org/10.1259/bjr.20160130
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
28281830
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article