Malignant paraganglioma of retroperitoneum. Light, electron microscopic and ultrasonographic study.
Publication/Presentation Date
6-1-1981
Abstract
A malignant retroperitoneal nonchromaffin paraganglioma in a thirty-four-year-old man was studied by light and electron microscopy. Histologically, the tumor cells displayed a tendency to surround granular, eosinophilic intercellular material and to form nests and pseudo-acini. Ultrastructurally, the tumor was composed of moderately well-differentiated epithelial cells intermixed with sparse sustentacular cells. An organoid pattern, reminiscent of the functional anatomic unit of nonchromaffin paraganglia, was seen occasionally. Epithelial cells formed pseudo-acini around dilated microvillous processes. These morphologic features are consistent with the neurocrestal origin of paragangliomas. The patient died ten months after presentation despite an initial favorable response to irradiation.
Volume
17
Issue
6
First Page
611
Last Page
615
ISSN
0090-4295
Published In/Presented At
Damjanov, I., Schocker, J. D., Katz, S. M., & Conroy, J. F. (1981). Malignant paraganglioma of retroperitoneum. Light, electron microscopic and ultrasonographic study. Urology, 17(6), 611–615. https://doi.org/10.1016/0090-4295(81)90090-x
Disciplines
Diagnosis | Medicine and Health Sciences | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Radiology
PubMedID
7245459
Department(s)
Department of Radiology and Diagnostic Medical Imaging
Document Type
Article