USF-LVHN SELECT
Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium.
Publication/Presentation Date
12-1-2022
Abstract
UNLABELLED: Length of stay (LOS) during index solid organ transplant impacts morbidity and healthcare costs. To date, there are no studies evaluating characteristics and outcomes of simultaneous liver-kidney transplant (SLKT) index hospitalization. We examined factors associated with LOS and mortality during index SLKT admission.
METHODS: Adult SLKT recipients between 2002 and 2017 at 6 transplant centers across 6 UNOS regions were retrospectively enrolled in the US-Multicenter SLKT Consortium. Multivariable regression analyses assessed predictors of SLKT LOS and death during index admission.
RESULTS: Median age of cohort (N = 570) was 58 y (interquartile range: 51-64); 63% male, 75% White, 32.3% hepatitis C, 23.3% alcohol-related, 20.1% nonalcoholic steatohepatitis with median MELD-Na at SLKT 28 (23-34). Seventy-one percent were hospitalized at the time of SLKT with median LOS pretransplant of 10 d. Majority of patients were discharged alive (N = 549; 96%)' and 36% were discharged to subacute rehab facility. LOS for index SLKT was 19 d (Q1: 10, Q3: 34 d). Female sex (
CONCLUSIONS: Despite excellent survival, index SLKT admission was associated with high-resource utilization with more than half the patients with LOS >2 wk and affected overall patient survival. Further investigation is needed to optimize healthcare resources for these patients in a financially strained healthcare landscape.
Volume
8
Issue
12
First Page
1408
Last Page
1408
ISSN
2373-8731
Published In/Presented At
Barman, P. M., Patel, Y. A., Xie, J., Zhang, M., Jo, J., Sinha, J., Answine, A., Schluger, A., Walter, K., Biggins, S. W., Cullaro, G., Wong, R., Lai, J. C., VanWagner, L. B., Magee, J., Verna, E. C., & Sharma, P. (2022). Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium. Transplantation direct, 8(12), e1408. https://doi.org/10.1097/TXD.0000000000001408
Disciplines
Medical Education | Medicine and Health Sciences
PubMedID
36398193
Department(s)
USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article