Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus.

Authors

Gabriella Blanco, Lehigh Valley Health NetworkFollow
Jianxiang Xue
Linto Thomas
Jessica A Dominguez Rieg
Dandan Sun
Adrienne Assmus
Robert A Fenton
Timo Rieg

Publication/Presentation Date

4-1-2025

Abstract

AIMS: The sodium-hydrogen exchanger isoform 1 (NHE1) is important for transepithelial Na

METHODS: We generated mice lacking NHE1 in epithelial cells throughout the kidney tubule/collecting duct (NHE1

RESULTS: In NHE1

CONCLUSION: Lack of NHE1 interferes with the Li

Volume

241

Issue

4

First Page

70029

Last Page

70029

ISSN

1748-1716

Published In/Presented At

Blanco, G., Xue, J., Thomas, L., Dominguez Rieg, J. A., Sun, D., Assmus, A., Fenton, R. A., & Rieg, T. (2025). Lack of renal NHE1 exacerbates lithium-induced nephrogenic diabetes insipidus. Acta physiologica (Oxford, England), 241(4), e70029. https://doi.org/10.1111/apha.70029

Disciplines

Medical Education | Medicine and Health Sciences

PubMedID

40123120

Department(s)

USF-LVHN SELECT Program, USF-LVHN SELECT Program Students

Document Type

Article