USF-LVHN SELECT
Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application.
Publication/Presentation Date
3-1-2021
Abstract
PURPOSE: To determine eye drop type and usage frequency and investigate risk factors for no eye drop use in individuals with symptomatic dry eye (DE) in Japan.
STUDY DESIGN: Crowdsourced observational study.
METHODS: This study was conducted using the DryEyeRhythm smartphone application between November 2016 and September 2019. Data collected included the type and frequency of eye drop use, demographics, medical history, lifestyle, and self-reported symptoms. Symptomatic DE was defined as an Ocular Surface Disease Index total score of ≥ 13. Risk factors for no eye drop use were identified using multivariate logistic regression analyses.
RESULTS: Among 2619 individuals with symptomatic DE, 1876 did not use eye drops. The most common eye drop type was artificial tears (53.4%), followed by hyaluronic acid 0.1% (33.1%) and diquafosol sodium 3% (18.7%). Risk factors (odds ratio [95% confidence interval]) for no eye drop use were age (0.97 [0.97-0.98]), body mass index (1.04 [1.01-1.07]), brain disease (0.38 [0.15-0.98]), collagen disease (0.30 [0.13-0.68]), mental illness other than depression and schizophrenia (0.65 [0.45-0.93]), cataract surgery (0.12 [0.02-0.59]), ophthalmic surgery other than cataract and laser-assisted in situ keratomileusis (0.55 [0.34-0.88]), current (0.47 [0.38-0.57]) or past (0.58 [0.43-0.77]) contact lens use, >8 h screen exposure time (1.38 [1.05-1.81]), (1.24 [1.01-1.52]) and >9 h (1.34 [1.04-1.72]) sleep time, and water intake (0.97 [0.94-0.98]).
CONCLUSION: Many participants with symptomatic DE did not use optimized eye drop treatment and identified risk factors for no eye drop use. The DryEyeRhythm application may help improve DE treatment.
Volume
65
Issue
2
First Page
271
Last Page
281
ISSN
1613-2246
Published In/Presented At
Eguchi, A., Inomata, T., Nakamura, M., Nagino, K., Iwagami, M., Sung, J., Midorikawa-Inomata, A., Okumura, Y., Fujio, K., Fujimoto, K., Miura, M., Akasaki, Y., Shokirova, H., Hirosawa, K., Kuwahara, M., Zhu, J., Dana, R., Murakami, A., & Kobayashi, H. (2021). Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application. Japanese journal of ophthalmology, 65(2), 271–281. https://doi.org/10.1007/s10384-020-00798-1
Disciplines
Medical Education | Medicine and Health Sciences
PubMedID
33411099
Department(s)
USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article