USF-LVHN SELECT
Prevalence and Characteristics of Dry Eye Disease After Cataract Surgery: A Systematic Review and Meta-Analysis.
Publication/Presentation Date
8-1-2022
Abstract
Dry eye disease (DED) after cataract surgery is associated with various risk factors, while causing a wide range of heterogeneous symptoms including decreased quality of vision. This systematic review and meta-analysis aimed to determine the prevalence and characteristics of DED after cataract surgery. We searched PubMed and EMBASE and included studies on patients with DED after cataract surgery, between January 2011 and June 2020. Study-specific estimates (DED prevalence rates after cataract surgery in patients without preexisting DED) were combined using one-group meta-analysis in a random-effects model. We included 36 studies published between 2013 and 2020. We included nine of these in the meta-analysis of DED prevalence after cataract surgery. Overall 37.4% (95% CI 22.6-52.3; 206/775) of patients without preexisting DED developed DED after cataract surgery. The risk factors for DED after cataract surgery included age, female sex, systemic diseases, systemic medications, psychiatric conditions, preexisting DED, meibomian gland dysfunction, preservatives in eye drops, surgery techniques, and lifestyle. DED severity peak occurred 1 day postoperatively and persisted for at least 1-12 months following cataract surgery; therefore, consistent follow-up for DED is warranted for at least 1 month after cataract surgery. Topical administration of preservative-free diquafosol tetrasodium solution and preoperative meibomian gland treatment were effective in preventing and treating DED following cataract surgery. As more than one-third of patients develop DED after cataract surgery, careful DED management and treatment is needed after cataract surgery to improve satisfaction and vision quality.
Volume
11
Issue
4
First Page
1309
Last Page
1332
ISSN
2193-8245
Published In/Presented At
Miura, M., Inomata, T., Nakamura, M., Sung, J., Nagino, K., Midorikawa-Inomata, A., Zhu, J., Fujimoto, K., Okumura, Y., Fujio, K., Hirosawa, K., Akasaki, Y., Kuwahara, M., Eguchi, A., Shokirova, H., & Murakami, A. (2022). Prevalence and Characteristics of Dry Eye Disease After Cataract Surgery: A Systematic Review and Meta-Analysis. Ophthalmology and therapy, 11(4), 1309–1332. https://doi.org/10.1007/s40123-022-00513-y
Disciplines
Medical Education | Medicine and Health Sciences
PubMedID
35534685
Department(s)
USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article