USF-LVHN SELECT
Nuisance bleeding complications in patients with cerebral aneurysm treated with Pipeline embolization device.
Publication/Presentation Date
3-1-2021
Abstract
BACKGROUND: Patients with cerebral aneurysms treated with the Pipeline embolization device (PED) are maintained on dual antiplatelet therapy (DAPT) to prevent thromboembolic complications. Rates of minor, "nuisance" bleeding in these patients remain unknown. We sought to evaluate the frequency and factors associated with this bleeding and its effect on DAPT compliance.
METHODS: We performed a multicenter retrospective cohort study on consecutive cases of intracranial aneurysms treated with PED. Patient characteristics, aneurysm characteristics, and bleeding complications were analyzed. Severity of bleeding was defined according to a previously published classification defining nuisance bleeding as easy bruising, bleeding from small cuts, petechia, and ecchymosis.
RESULTS: 245 PED aneurysm procedures on 243 patients were retrospectively collected from three academic centers over a 4.25-year period. Sixty-seven patients (27%) had nuisance bleeds. Patients with a higher risk of nuisance bleeding were older (59.1±3.4 vs . 54.7±2.2, P=0.032). Patients with nuisance bleeds were more likely to have their DAPT regimen changed or dose lowered (29% vs 8.3%, P
Volume
13
Issue
3
First Page
247
Last Page
250
ISSN
1759-8486
Published In/Presented At
Pressman, E., De la Garza, C. A., Chin, F., Fishbein, J., Waqas, M., Siddiqui, A., Snyder, K., Davies, J. M., Levy, E., Kan, P., Ren, Z., & Mokin, M. (2021). Nuisance bleeding complications in patients with cerebral aneurysm treated with Pipeline embolization device. Journal of neurointerventional surgery, 13(3), 247–250. https://doi.org/10.1136/neurintsurg-2020-016245
Disciplines
Medical Education | Medicine and Health Sciences
PubMedID
32620576
Department(s)
USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article