USF-LVHN SELECT
Impact of Gut Bacterial Metabolites on Psoriasis and Psoriatic Arthritis: Current Status and Future Perspectives.
Publication/Presentation Date
9-1-2023
Abstract
There is growing evidence that supports a role of gut dysbiosis in the pathogenesis of psoriasis (Pso). Thus, probiotic supplementation and fecal microbiota transplantation may serve as promising preventive and therapeutic strategies for patients with Pso. One of the basic mechanisms through which the gut microbiota interacts with the host is through bacteria-derived metabolites, usually intermediate or end products produced by microbial metabolism. In this study, we provide an up-to-date review of the most recent literature on microbial-derived metabolites and highlight their roles in the immune system, with a special focus on Pso and one of its most common comorbidities, psoriatic arthritis.
Volume
143
Issue
9
First Page
1657
Last Page
1666
ISSN
1523-1747
Published In/Presented At
Lai, Y., Wu, X., Chao, E., Bloomstein, J. D., Wei, G., Hwang, S. T., & Shi, Z. (2023). Impact of Gut Bacterial Metabolites on Psoriasis and Psoriatic Arthritis: Current Status and Future Perspectives. The Journal of investigative dermatology, 143(9), 1657–1666. https://doi.org/10.1016/j.jid.2023.05.012
Disciplines
Medical Education | Medicine and Health Sciences
PubMedID
37422760
Department(s)
USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article