USF-LVHN SELECT
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives.
Publication/Presentation Date
11-24-2023
Abstract
PURPOSE OF REVIEW: This review summarizes current findings regarding limb amputation within the context of cancer, especially in osteosarcomas and other bony malignancies. We seek to answer the question of how amputation is utilized in the contemporary management of cancer as well as explore current advances in limb-sparing techniques.
RECENT FINDINGS: The latest research on amputation has been sparse given its extensive history and application. However, new research has shown that rotationplasty, osseointegration, targeted muscle reinnervation (TMR), and regenerative peripheral nerve interfaces (RPNI) can provide patients with better functional outcomes than traditional amputation. While limb-sparing surgeries are the mainstay for managing musculoskeletal malignancies, limb amputation is useful as a palliative technique or as a primary treatment modality for more complex cancers. Currently, rotationplasty and osseointegration have been valuable limb-sparing techniques with osseointegration continuing to develop in recent years. TMR and RPNI have also been of interest in the modern management of patients requiring full or partial amputations, allowing for better control over myoelectric prostheses.
ISSN
1534-6269
Published In/Presented At
Huynh, T. H. N., Kuruvilla, D. R., Nester, M. D., Zervoudakis, G., Letson, G. D., Joyce, D. M., Binitie, O. T., & Lazarides, A. L. (2023). Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives. Current oncology reports, 10.1007/s11912-023-01475-5. Advance online publication. https://doi.org/10.1007/s11912-023-01475-5
Disciplines
Medical Education | Medicine and Health Sciences
PubMedID
37999825
Department(s)
USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article