Two-Year Clinical Outcomes After Multipoint Impedance-Controlled Radiofrequency Ablation of the Posterior Nasal Nerve for Treatment of Chronic Rhinitis.

Publication/Presentation Date

10-9-2025

Abstract

OBJECTIVE: A person's quality of life can be deeply impacted by chronic rhinitis. We report 2-year outcomes in patients after treatment using a novel, multipoint, impedance-controlled, radiofrequency ablation device.

METHODS: A prospective, multicenter, single-arm clinical study of posterior nasal nerve ablation in adults with chronic rhinitis. Efficacy assessments included the reflective total nasal symptom score (rTNSS), postnasal drip, cough, Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7), nasal obstruction symptom evaluation (NOSE), and mini-Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ).

RESULTS: Seventy-five of 80 (94%) participants completed 2-year follow-up. Statistically significant improvements were observed in rhinitis symptoms, postnasal drip, cough, ear symptoms, and quality of life as evidenced by the mean change in rTNSS (-4.3), postnasal drip (-0.9), cough (-0.7), ETDQ-7 (-1.1), NOSE (-31.7), and mini-RQLQ (-1.7;

CONCLUSIONS: The data demonstrate consistent long-term efficacy and safety of a multipoint, impedance-controlled, radiofrequency ablation device for the treatment of chronic rhinitis. Significant improvements were observed in rhinitis symptoms, postnasal drip, cough, ear symptoms, and quality of life through 2-year follow-up.

STUDY REGISTRATION: www.

CLINICALTRIALS: gov. Unique identifier NCT05591989.

First Page

1455613251382759

Last Page

1455613251382759

ISSN

1942-7522

Disciplines

Medicine and Health Sciences

PubMedID

41065547

Department(s)

Department of Surgery

Document Type

Article

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