Prevalence of periocular depigmentation after repeated botulinum toxin A injections in African American patients.
Publication/Presentation Date
3-1-1999
Abstract
Botulinum toxin A (Botox), administered by subcutaneous or intramuscular injection, is the most commonly used and most successful medication for many craniocervical dystonias. Although some patients experience side effects related to the neuroparalytic action of the medication, these side effects are temporary. In 1996, permanent periocular cutaneous depigmentation was reported in three white patients after repeated Botox injections, suggesting that loss or alteration of melanin pigment might be a permanent side effect of long-term Botox injections. The authors examined and photographed 26 African American patients who were receiving periocular Botox injections for hemifacial spasm and essential blepharospasm. The authors found no evidence of periocular cutaneous depigmentation in any of these patients.
Volume
19
Issue
1
First Page
7
Last Page
9
ISSN
1070-8022
Published In/Presented At
Roehm, P. C., Perry, J. D., Girkin, C. A., & Miller, N. R. (1999). Prevalence of periocular depigmentation after repeated botulinum toxin A injections in African American patients. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 19(1), 7–9.
Disciplines
Medicine and Health Sciences
PubMedID
10098540
Department(s)
Department of Surgery
Document Type
Article