Preoperative MELD-XI Score and Risk of Heart Failure After Mitral Valve Surgery for Degenerative Mitral Regurgitation.
Publication/Presentation Date
6-1-2026
Abstract
BACKGROUND: This study aimed to assess the association between the Model for End-Stage Liver Disease excluding international normalized ratio (MELD-XI) score and heart failure (HF) after isolated mitral valve surgery for degenerative mitral valve regurgitation (dMR).
METHODS: Patients undergoing mitral valve surgery for dMR were divided into groups of high MELD-XI score (>11, n = 28) and low MELD-XI score (≤11, n = 144). The primary end point was early HF events, defined as operative mortality, use of mechanical circulatory support, and prolonged use of inotropic agents after the surgery. The secondary end point was a composite outcome consisting of all-cause mortality and HF admission. The median follow-up period was 338 (70-789) days.
RESULTS: Thirty-day mortality rate was 0.7% in the low MELD-XI score group and 3.6% in the high MELD-XI score group (
CONCLUSIONS: In patients undergoing isolated mitral valve surgery for dMR, elevated preoperative MELD-XI score was associated with an increased risk of early HF events and the composite outcome.
Volume
4
Issue
2
First Page
607
Last Page
612
ISSN
2772-9931
Published In/Presented At
Nakamura, Y., Sakata, T., Koeneman, S. H., Rajagopal, K., Tchantchaleishvili, V., Plestis, K. A., Entwistle, J. W., 3rd, Bavaria, J. E., & Suri, R. M. (2025). Preoperative MELD-XI Score and Risk of Heart Failure After Mitral Valve Surgery for Degenerative Mitral Regurgitation. Annals of thoracic surgery short reports, 4(2), 607–612. https://doi.org/10.1016/j.atssr.2025.09.035
Disciplines
Medicine and Health Sciences
PubMedID
42267041
Department(s)
Department of Surgery
Document Type
Article