Outcomes of lung transplants utilizing donors from outside the continental United States.
Publication/Presentation Date
8-1-2025
Abstract
BACKGROUND: Efforts to expand the lung transplant donor pool have included re-evaluating geographic restrictions and accepting longer distances between donor and recipient centers. We evaluated the use of organs from donors outside the continental United States.
METHODS: Adult lung-only transplants from 2005-2022 in the United Network for Organ Sharing database were included and categorized based on donor location (mainland US vs nonmainland). Survival out to 1 and 5 years post-transplant was evaluated using time-to-event analysis and multivariable Cox regression.
RESULTS: Of 35,638 transplants, 389 (1.1%) utilized nonmainland donors. Nonmainland donors were younger (median 28 vs 33 years,
CONCLUSIONS: Transplants utilizing nonmainland donors had lower-risk donor and recipient characteristics. Despite greater distances and ischemic times, these transplants had similar post-transplant survival compared to transplants using mainland donors, supporting the use of select donors from outside the mainland United States.
Volume
9
First Page
100324
Last Page
100324
ISSN
2950-1334
Published In/Presented At
Jenkins, R. T., Larson, E. L., Zhou, A. L., Ruck, J. M., Farhat, D. J., Rached, H., Kassam, A. F., Merlo, C. A., Riojas, R. A., & Bush, E. L. (2025). Outcomes of lung transplants utilizing donors from outside the continental United States. JHLT open, 9, 100324. https://doi.org/10.1016/j.jhlto.2025.100324
Disciplines
Medicine and Health Sciences
PubMedID
40687313
Department(s)
Department of Surgery
Document Type
Article