Prevention of surgical site infections in high-risk patients with laparotomy incisions using negative-pressure therapy.
Publication/Presentation Date
6-1-2013
Abstract
BACKGROUND: This study evaluates the efficacy of negative-pressure therapy (NPT) in preventing surgical site infections (SSIs) in high-risk surgical oncology patients.
METHODS: A retrospective analysis of 191 operations for colorectal, pancreatic, or peritoneal surface malignancies was performed. Incisional NPT was used in patients with multiple SSI risk factors. Rates of SSIs were compared with patients treated with a standard sterile dressing (SSD).
RESULTS: NPT was used in 104 patients, whereas SSDs were used in 87 patients. Despite being at an increased risk of SSI, patients treated with NPT developed fewer superficial incisional SSIs compared with SSD patients (6.7% vs 19.5%, P = .015). In a subgroup analysis of clean-contaminated cases, NPT was associated with fewer superficial incisional SSIs (6.0% vs 27.4%, P = .001), fewer total SSIs (16.0% vs 35.5%, P = .011), and fewer wound openings for any reason (16.0% vs 35.5%, P = .011).
CONCLUSIONS: Our findings suggest that NPT decreases SSIs in high-risk surgical oncology patients.
Volume
205
Issue
6
First Page
647
Last Page
654
ISSN
1879-1883
Published In/Presented At
Blackham, A. U., Farrah, J. P., McCoy, T. P., Schmidt, B. S., & Shen, P. (2013). Prevention of surgical site infections in high-risk patients with laparotomy incisions using negative-pressure therapy. American journal of surgery, 205(6), 647–654. https://doi.org/10.1016/j.amjsurg.2012.06.007
Disciplines
Medicine and Health Sciences
PubMedID
23375758
Department(s)
Department of Surgery
Document Type
Article