Decreased blood transfusion following revision total knee arthroplasty using tranexamic acid.

Publication/Presentation Date

9-1-2014

Abstract

Tranexamic acid (TXA) has been used successfully in primary total knee arthroplasty (TKA) to minimize blood loss and transfusions. The purpose of this study is to determine its efficacy in patients undergoing revision TKA. In a retrospective review of 111 patients (68 control and 43 TXA), treatment patients receiving a single intravenous TXA dose of 10mg/kg required less transfusions (P=0.03) and less total blood units consumed than controls (P=0.03). When stratified by type of revision, treatment patients undergoing femoral and tibial component revision had lower transfusion rates than the controls (P=0.03). Given the drawbacks of allogenic blood transfusion, we highly recommend the use of TXA in revision TKA, especially when both components are being revised.

Volume

29

Issue

9 Suppl

First Page

182

Last Page

185

ISSN

1532-8406

Disciplines

Medicine and Health Sciences

PubMedID

25015759

Department(s)

Department of Surgery

Document Type

Article

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