Prognostic significance of microalbuminuria in postdiarrheal hemolytic uremic syndrome.
Publication/Presentation Date
1-1-2007
Abstract
Patients who survive the acute phase of postdiarrheal hemolytic uremic syndrome (D+ HUS) may develop renal complications after years of apparent recovery. The optimal regimen for monitoring these children is unclear. We therefore determined if screening for microalbuminuria, in the absence of overt proteinuria at follow-up, increased the sensitivity for predicting long-term renal-related sequelae. We found that screening for microalbuminurea, within the first 6-18 months following an episode of HUS, increased the sensitivity for predicting later sequelae from 22 to 66.7%, compared to screening for overt proteinuria alone. These findings, if confirmed by a larger cohort with more years of follow-up, may facilitate early initiation of intervention strategies designed to reduce progressive renal damage.
Volume
22
Issue
1
First Page
117
Last Page
120
ISSN
0931-041X
Published In/Presented At
Lou-Meda, R., Oakes, R. S., Gilstrap, J. N., Williams, C. G., & Siegler, R. L. (2007). Prognostic significance of microalbuminuria in postdiarrheal hemolytic uremic syndrome. Pediatric nephrology (Berlin, Germany), 22(1), 117–120. https://doi.org/10.1007/s00467-006-0283-3
Disciplines
Medicine and Health Sciences
PubMedID
16967283
Department(s)
Department of Surgery, Department of Surgery Residents, Fellows and Residents
Document Type
Article