Linking ADHD to the Neural Circuitry of Attention.
Publication/Presentation Date
6-1-2017
Abstract
Attention deficit hyperactivity disorder (ADHD) is a complex condition with a heterogeneous presentation. Current diagnosis is primarily based on subjective experience and observer reports of behavioral symptoms - an approach that has significant limitations. Many studies show that individuals with ADHD exhibit poorer performance on cognitive tasks than neurotypical controls, and at least seven main functional domains appear to be implicated in ADHD. We discuss the underlying neural mechanisms of cognitive functions associated with ADHD, with emphasis on the neural basis of selective attention, demonstrating the feasibility of basic research approaches for further understanding cognitive behavioral processes as they relate to human psychopathology. The study of circuit-level mechanisms underlying executive functions in nonhuman primates holds promise for advancing our understanding, and ultimately the treatment, of ADHD.
Volume
21
Issue
6
First Page
474
Last Page
488
ISSN
1879-307X
Published In/Presented At
Mueller, A., Hong, D. S., Shepard, S., & Moore, T. (2017). Linking ADHD to the Neural Circuitry of Attention. Trends in cognitive sciences, 21(6), 474–488. https://doi.org/10.1016/j.tics.2017.03.009
Disciplines
Medicine and Health Sciences
PubMedID
28483638
Department(s)
Department of Pediatrics, Department of Surgery
Document Type
Article