Angiotensin-converting enzyme inhibitor induced angioedema of the head and neck.

Publication/Presentation Date

1-1-1990

Abstract

Angiotensin-converting enzyme (ACE) inhibitors are now in widespread use for the treatment of essential and renovascular hypertension. Consequently, angioedema, an uncommon complication of ACE inhibitor therapy is being encountered with increasing frequency. Since ACE inhibitor angioedema predominantly involves the face, lips, oral cavity, and occasionally the larynx the otolaryngologist is often consulted to evaluate affected patients. Treatment ranges from simple cessation of the drug to emergent airway intervention. The pertinent pharmacologic properties of ACE inhibitors and the pathophysiology of angioedema are discussed. The authors' experience with the evaluation and treatment of ACE inhibitor induced angioedema is presented.

Volume

42

First Page

998

Last Page

1001

ISSN

0048-3206

Disciplines

Medicine and Health Sciences

PubMedID

2085001

Department(s)

Department of Surgery, Division of Otolaryngology

Document Type

Article

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