Modern Appraisal of Patency and Complications in Cerebral Bypass Surgery: A Single Institution Experience.
Publication/Presentation Date
6-1-2022
Abstract
BACKGROUND: Cerebral bypass is a valuable surgical technique in well-selected patient populations. Updated clinical guidelines and improved surgical techniques warrant a contemporary reevaluation of the complications and patency to inform clinical practice and enhance postoperative patient care.
OBJECTIVE: To assess the complication rates and postoperative graft patency for the 3 most common indications for bypass surgery: moyamoya disease, intracranial atherosclerosis, and intracranial aneurysms.
METHODS: Perioperative notes of 175 consecutive bypass patients at a single institution were retrospectively identified to evaluate the clinical course and complications of surgery.
RESULTS: The rate of total postoperative complications between moyamoya disease (9 of 98, 9.2%), intracranial atherosclerotic disease (7 of 57, 12.3%), and intracranial aneurysm (4 of 20, 20%) was not statistically different (P = .33). Immediate postoperative bypass patency was significantly higher in moyamoya disease (90 of 96, 93.8%) and intracranial atherosclerotic disease (48 of 51, 94.1%) than in intracranial aneurysm (13 of 18, 72.2%; P = .02). Intravenous heparin administration during bypass suturing was negatively associated with immediate postoperative patency (87% heparin patency vs 99% no heparin patency; P = .02). Double-barrel bypass trended toward an increased risk of wound healing complications (2 of 13, 15.4%) compared with the single-barrel bypass technique (4 of 156, 2.6%; P = .07).
CONCLUSION: Cerebral bypass surgery remains an excellent surgical treatment for moyamoya disease, intracranial atherosclerosis, and intracranial aneurysms. This study suggests bypass is safer in moyamoya disease and intracranial atherosclerosis. Additional studies to clarify the risk of single-barrel vs double-barrel bypass and intraoperative heparin-stratified complications may be beneficial.
Volume
22
Issue
6
First Page
355
Last Page
363
ISSN
2332-4260
Published In/Presented At
Farooq, J., Heller, R. S., Noureldine, M. H. A., Wang, Z. J., Wei, G., Mhaskar, R., Ren, Z., van Loveren, H., Lau, T., & Agazzi, S. (2022). Modern Appraisal of Patency and Complications in Cerebral Bypass Surgery: A Single Institution Experience. Operative neurosurgery (Hagerstown, Md.), 22(6), 355–363. https://doi.org/10.1227/ons.0000000000000177
Disciplines
Medicine and Health Sciences
PubMedID
35404307
Department(s)
Department of Surgery, USF-LVHN SELECT Program, USF-LVHN SELECT Program Students
Document Type
Article