Primary diffuse large B cell lymphoma of the optic chiasm in an immunocompetent patient.
Publication/Presentation Date
7-30-2021
Abstract
Primary lymphoma of the visual pathway is rare, especially at the chiasm. Very few cases have been reported. The lesion is frequently confused with an optic-hypothalamic glioma. A 55-year-old man was found disoriented at his home by a friend and evaluated with a brain MRI which demonstrated an expansile mass located at the optic chiasm and hypothalamus level. The principal differential was a high-grade hypothalamic glioma due to the contrast enhancement. A biopsy of the chiasmal lesion was performed. Histological diagnosis of the lesion was compatible with a diffuse large B cell lymphoma. He was started on methotrexate and rituximab; however, his clinical course kept deteriorating, and he died 64 days after his presentation. All prior cases of primary lymphoma of the chiasm are reviewed.
Volume
14
Issue
7
ISSN
1757-790X
Published In/Presented At
De Jesus, O., Rios-Vicil, C., Gómez-González, F. M., & Vélez, R. (2021). Primary diffuse large B cell lymphoma of the optic chiasm in an immunocompetent patient. BMJ case reports, 14(7), e243307. https://doi.org/10.1136/bcr-2021-243307
Disciplines
Medicine and Health Sciences
PubMedID
34330724
Department(s)
Department of Surgery, Department of Surgery Residents, Fellows and Residents
Document Type
Article