Final diagnosis by fine-needle aspiration biopsy for definitive operation in breast cancer.
Publication/Presentation Date
11-1-1987
Abstract
This work has been based on 15 years experience with more than 10,000 needle aspiration biopsies of the breast. Fine-needle aspiration biopsy was used in place of open breast biopsy for definitive operation in breast cancer. Our experience with 2,623 aspiration biopsies over a 3 year period has been reviewed. There was a total of 323 cancers, of which 257 (80 percent) were unequivocally diagnosed by fine-needle aspiration biopsy. Definitive operation was performed in 244 of these patients (95 percent) without open biopsy. Thirteen had an excisional biopsy before definitive operation at the request of the referring physician. The sensitivity was 80 percent and the specificity was 98 percent. There were no false-positive diagnoses. The positive predictive value was 100 percent. False-negative diagnoses were made in 9 percent of the patients, half of whom had nonpalpable carcinomas. Our experience shows that fine-needle aspiration biopsy is accurate in the diagnosis of breast cancer, and when the finding is positive, it can be used for definitive breast operation, eliminating the need for open biopsy. A management algorithm has also been presented herein.
Volume
154
Issue
5
First Page
470
Last Page
474
ISSN
0002-9610
Published In/Presented At
Sheikh, F. A., Tinkoff, G. H., Kline, T. S., & Neal, H. S. (1987). Final diagnosis by fine-needle aspiration biopsy for definitive operation in breast cancer. American journal of surgery, 154(5), 470–474. https://doi.org/10.1016/0002-9610(87)90254-6
Disciplines
Medicine and Health Sciences
PubMedID
3674292
Department(s)
Department of Surgery
Document Type
Article