Volumetric Study of Nonfunctioning Pituitary Adenomas: Predictors of Gross Total Resection.
Publication/Presentation Date
3-1-2021
Abstract
OBJECTIVE: Despite the efforts made to determine the achieved resection grade after pituitary adenoma surgery, there is a high level of disagreement among all the available classifications and measurement methods used. Our objective is to identify the factors that preoperatively could predict a gross total resection (GTR) of a clinically nonfunctioning pituitary adenoma through an endoscopic endonasal approach.
METHODS: Across 100 surgeries, we analyzed epidemiologic and clinical data, radiologic relevant data, extent of resection (EOR), and postoperative outcomes. The EOR was measured objectively through an accurate volumetric analysis.
RESULTS: The median presurgical volume was 8.58 cm
CONCLUSIONS: Knosp grade (P < 0.001; odds ratio [OR], 25.65; 95% confidence interval, 7.19-91.52) is the most predictive factor for performing a GTR of nonfunctioning pituitary adenoma. Previous pituitary surgery (P = 0.023; OR, 5.81) and an isointense T2-weighted signal (P = 0.034; OR, 3.75) also negatively influenced the chances of GTR. We highlight the influence of T2-weighted signal in the chances of GTR.
Volume
147
First Page
206
Last Page
206
ISSN
1878-8769
Published In/Presented At
Pérez-López, C., Palpán, A. J., Saez-Alegre, M., Zamarrón, Á., Alfonso, C., Álvarez-Escola, C., & Isla, A. (2021). Volumetric Study of Nonfunctioning Pituitary Adenomas: Predictors of Gross Total Resection. World neurosurgery, 147, e206–e214. https://doi.org/10.1016/j.wneu.2020.12.020
Disciplines
Medicine and Health Sciences
PubMedID
33309892
Department(s)
Department of Surgery, Fellows and Residents, Department of Surgery Residents
Document Type
Article