Seven Microaneurysms: Description of an Experimental Rodent Model for Neurovascular Training.
Publication/Presentation Date
1-1-2021
Abstract
AIM: To demonstrate the microsurgical procedures, and to evaluate the feasibility of living models of experimental neurovascular training by developing new complex vascular exercises mimicking the most common intracranial aneurysms.
MATERIAL AND METHODS: The procedures were performed under a Zeiss (OPMI pico f170) microscope using basic microsurgery instruments, 10/0 Nylon and blue Polypropylene micro-sutures. We selected adult albino Wistar rats weighing between 258 and 471g each. Seven different aneurysm types were created using carotid, jugular, cava, aorta and femoral vessels.
RESULTS: Seven types of aneurysm were designed and created in the rat with a high-medium successful rate. There are differences in terms of realism and the difficulty of performance, according to the different types: lateral wall, bifurcation, top of the basilar, fusiform, fusiform + involved branch, Anterior Communicating Artery (ACoA) and giant. The steps and technical issues to produce these exercises are described.
CONCLUSION: We show the feasibility of creating several types of aneurysm using different vessels in a rodent model. Training on these models help to improve microsurgical skills, allowing safe practice for neurosurgeons in all stages of their career.
Volume
31
Issue
2
First Page
217
Last Page
222
ISSN
1019-5149
Published In/Presented At
Feijoo, P. G., Benito, F., Kalra, N., Cárdenas, G. P., Alegre, M. S., Sánchez, C. V., Domínguez, V. R., & Frade, J. (2021). Seven Microaneurysms: Description of an Experimental Rodent Model for Neurovascular Training. Turkish neurosurgery, 31(2), 217–222. https://doi.org/10.5137/1019-5149.JTN.30673-20.1
Disciplines
Medicine and Health Sciences
PubMedID
33624274
Department(s)
Department of Surgery
Document Type
Article