High-frequency percussive ventilation improves oxygenation in patients with ARDS.
Publication/Presentation Date
8-1-1999
Abstract
STUDY OBJECTIVES: To evaluate changes in respiratory and hemodynamic function of patients with ARDS and requiring high-frequency percussive ventilation (HFPV) after failure of conventional ventilation (CV).
DESIGN: Retrospective case series.
SETTING: Surgical ICU (SICU) and medical ICU (MICU) of an academic county facility.
MEASUREMENTS AND RESULTS: Thirty-two consecutive patients with ARDS (20 from SICU, 12 from MICU) who were unresponsive to at least 48 h of CV and were switched to HFPV were studied. Data on respiratory and hemodynamic parameters were collected during the 48 h preceding and the 48 h after institution of HFPV and compared. Between the period of CV and the period of HFPV, the ratio of PaO2 to the fraction of inspired oxygen (F(IO2)) increased ([mean+/-SE] 130+/-8 vs. 172+/-17; p = 0.027), peak inspiratory pressure (PIP) decreased (39.5+/-1.7 vs. 32.5+/-1.9 mm Hg; p = 0.002), and mean airway pressure(MAP) increased (19.2+/-1.2 vs. 27.5+/-1.4 mm Hg; p
CONCLUSION: The HFPV improves oxygenation by increasing MAP and decreasing PIP. This improvement is achieved soon after institution of HFPV and is maintained without affecting hemodynamics.
Volume
116
Issue
2
First Page
440
Last Page
446
ISSN
0012-3692
Published In/Presented At
Velmahos, G. C., Chan, L. S., Tatevossian, R., Cornwell, E. E., 3rd, Dougherty, W. R., Escudero, J., & Demetriades, D. (1999). High-frequency percussive ventilation improves oxygenation in patients with ARDS. Chest, 116(2), 440–446. https://doi.org/10.1378/chest.116.2.440
Disciplines
Medicine and Health Sciences
PubMedID
10453874
Department(s)
Department of Surgery
Document Type
Article