Clinical predictors for prolonged intensive care unit stay in adults undergoing thoracic aortic surgery requiring deep hypothermic circulatory arrest.

Publication/Presentation Date

2-1-2006

Abstract

OBJECTIVE: The purpose of this study was to describe clinical predictors for prolonged length of stay in the intensive care unit (PLOS-ICU) after adult thoracic aortic surgery requiring standardized deep hypothermic circulatory arrest (DHCA); and to determine the incidence of PLOS-ICU after DHCA, univariate predictors for PLOS-ICU, and multivariate predictors for PLOS-ICU.

STUDY DESIGN: A retrospective and observational study. PLOS-ICU was defined as longer than 5 days in the ICU.

STUDY SETTING: Cardiothoracic operating rooms and the ICU.

PARTICIPANTS: All adults requiring thoracic aortic repair with DHCA INTERVENTIONS: None.

MAIN RESULTS: The cohort size was 144. The incidence of PLOS-ICU was 27.8%. The mortality rate was 11.1%. Univariate predictors for PLOS-ICU were age, stroke, DHCA duration, vasopressor dependence >72 hours, mediastinal re-exploration for bleeding, and renal dysfunction. Multivariate predictors for PLOS-ICU were stroke, vasopressor dependence >72 hours, and renal dysfunction.

CONCLUSIONS: PLOS-ICU after DHCA is common. The identified multivariate predictors merit further hypothesis-driven research to enhance perioperative protection of the brain, kidney, and cardiovascular system.

Volume

20

Issue

1

First Page

8

Last Page

13

ISSN

1053-0770

Disciplines

Medicine and Health Sciences

PubMedID

16458206

Department(s)

Department of Surgery

Document Type

Article

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