Impact of image analysis methodology on diagnostic and surgical classification of patients with thoracic aortic aneurysms.
Publication/Presentation Date
9-1-2011
Abstract
BACKGROUND: For patients with thoracic aortic aneurysms (TAA), aortic size on imaging is widely used to guide clinical decision making. This study examined the impact of methodological variance on aortic quantification.
METHODS: We studied enrollees in the National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions. Aortic size on computed tomography was quantified by 2 linear methods; cross-sectional dimensions in axial (AX) and double oblique (DO) plane. Calculated area was compared to planimetry. Established cutoffs (area/height>10 cm2/m, diameter≥5 cm) for prophylactic TAA repair were used to compare surgical eligibility by each method.
RESULTS: Fifty subjects were studied. Aortic size differed between AX and DO at all locations (p≤0.001), with magnitude greatest at the sinotubular junction (4.8±1.1 vs 4.0±1.0 cm, p
CONCLUSIONS: Established linear methods for aortic measurement yield different results that impact surgical eligibility. DO yielded improved agreement with planimetry and differed with AX in proportion to aortic geometric obliquity. Findings support DO measurements for imaging evaluation of subjects with TAA.
Volume
92
Issue
3
First Page
904
Last Page
912
ISSN
1552-6259
Published In/Presented At
Mendoza, D. D., Kochar, M., Devereux, R. B., Basson, C. T., Min, J. K., Holmes, K., Dietz, H. C., Milewicz, D. M., LeMaire, S. A., Pyeritz, R. E., Bavaria, J. E., Maslen, C. L., Song, H., Kroner, B. L., Eagle, K. A., Weinsaft, J. W., & GenTAC (National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions) Study Investigators (2011). Impact of image analysis methodology on diagnostic and surgical classification of patients with thoracic aortic aneurysms. The Annals of thoracic surgery, 92(3), 904–912. https://doi.org/10.1016/j.athoracsur.2011.03.130
Disciplines
Medicine and Health Sciences
PubMedID
21723533
Department(s)
Department of Surgery
Document Type
Article