Five-year outcomes of endovascular repair of complicated acute type B aortic dissections.
Publication/Presentation Date
2-1-2022
Abstract
OBJECTIVE: Thoracic endovascular aortic repair is the standard of care for acute complicated type B aortic dissections, but long-term single-device outcomes are limited.
METHODS: Fifty patients were treated with the Valiant Captivia thoracic stent graft (Medtronic Inc, Santa Rosa, Calif) for acute complicated type B aortic dissections in this prospective, nonrandomized Dissection Trial. All-cause mortality, secondary procedures, and serious adverse events were assessed, and a core lab evaluated images for aortic remodeling.
RESULTS: Compliance for both clinical and imaging follow-up was 78% (18 out of 23) for the available patients at 5 years. Notable baseline characteristics were 86% of patients (43 out of 50) had malperfusion, 20% (10 out of 50) had ruptures, and 94% (46 out of 49) had DeBakey class IIIB dissections. The 5-year freedom from dissection-related mortality, secondary procedures related to the dissection, and endoleaks was 83%, 86%, and 85%, respectively. After 5 years, 89% of patients (16 out of 18) had a completely thrombosed false lumen in the stented segment of the aorta and the true lumen diameter over the length of stent graft was stable or increased for 94% of patients (16 out of 17) while the false lumen diameter was stable or decreased in 77% (13 out of 17) after 5 years.
CONCLUSIONS: In the Dissection Trial, patients experienced positive and sustained measures of aortic remodeling. Survival outcomes, need for secondary procedures, and adverse event rates were consistent with previous thoracic endovascular aortic repair studies. Although limitations exist with the follow-up compliance, the Valiant Captivia thoracic stent graft system was effective in the long-term management of acute complicated type B aortic dissections in this patient population with a challenging condition.
Volume
163
Issue
2
First Page
539
Last Page
548
ISSN
1097-685X
Published In/Presented At
Bavaria, J. E., Brinkman, W. T., Hughes, G. C., Shah, A. S., Charlton-Ouw, K. M., Azizzadeh, A., & White, R. A. (2022). Five-year outcomes of endovascular repair of complicated acute type B aortic dissections. The Journal of thoracic and cardiovascular surgery, 163(2), 539–548.e2. https://doi.org/10.1016/j.jtcvs.2020.03.162
Disciplines
Medicine and Health Sciences
PubMedID
32654872
Department(s)
Department of Surgery
Document Type
Article