Strain estimation in aortic roots from 4D echocardiographic images using medial modeling and deformable registration.
Publication/Presentation Date
7-1-2023
Abstract
Even though the central role of mechanics in the cardiovascular system is widely recognized, estimating mechanical deformation and strains in-vivo remains an ongoing practical challenge. Herein, we present a semi-automated framework to estimate strains from four-dimensional (4D) echocardiographic images and apply it to the aortic roots of patients with normal trileaflet aortic valves (TAV) and congenital bicuspid aortic valves (BAV). The method is based on fully nonlinear shell-based kinematics, which divides the strains into in-plane (shear and dilatational) and out-of-plane components. The results indicate that, even for size-matched non-aneurysmal aortic roots, BAV patients experience larger regional shear strains in their aortic roots. This elevated strains might be a contributing factor to the higher risk of aneurysm development in BAV patients. The proposed framework is openly available and applicable to any tubular structures.
Volume
87
First Page
102804
Last Page
102804
ISSN
1361-8423
Published In/Presented At
Aggarwal, A., Mortensen, P., Hao, J., Kaczmarczyk, Ł., Cheung, A. T., Al Ghofaily, L., Gorman, R. C., Desai, N. D., Bavaria, J. E., & Pouch, A. M. (2023). Strain estimation in aortic roots from 4D echocardiographic images using medial modeling and deformable registration. Medical image analysis, 87, 102804. https://doi.org/10.1016/j.media.2023.102804
Disciplines
Medicine and Health Sciences
PubMedID
37060701
Department(s)
Department of Surgery
Document Type
Article