[Value of oncologic follow-up of patients operated for colorectal cancer. A prospective study of 1000 patients].
Publication/Presentation Date
7-1-1997
Abstract
OBJECTIVE: The purpose of our prospective study was to evaluate the contribution of follow-up in resected colorectal cancer.
METHODS: One-thousand patients with colorectal adenocarcinoma who underwent radial resection from January 1975 to January 1990 were prospectively divided into two groups: the first group (n = 442, 42%) entered a 5-year follow-up protocol and the second group (n = 558, 56%) was free to make unscheduled visits in case of symptoms.
RESULTS: Recurrence was found in 31.5% of the patients in the first group compared with 33% in the second group. Chorioembryonic antigen was the most accurate test detecting recurrence: 77% of the cases (97% for hepatic metastasis). Surgical resection of recurrent tumors was performed in 37% of the group 1 patients (curative resection in 15%) and in 9% (curative resection in 1.5%) of the group 2 patients (p < 0.001). 5-year survival after recurrence in group 1 was 11.5% versus 1% in group 2 (p < 0.01).
CONCLUSION: These results emphasize the rational for a follow-up program in patients undergoing surgery for colorectal cancer.
Volume
134
Issue
2
First Page
45
Last Page
50
ISSN
0021-7697
Published In/Presented At
Arnaud, J. P., Cervi, C., Bergamaschi, R., & Tuech, J. J. (1997). Intérêt d'un suivi carcinologique chez les patients opérés d'un cancer colo-rectal. Etude prospective portant sur 1,000 patients [Value of oncologic follow-up of patients operated for colorectal cancer. A prospective study of 1000 patients]. Journal de chirurgie, 134(2), 45–50.
Disciplines
Medicine and Health Sciences
PubMedID
9378783
Department(s)
Department of Surgery
Document Type
Article