The paradoxical functions of B cells and antibodies in transplantation.
Publication/Presentation Date
2-1-2013
Abstract
Scarcely anyone would dispute that donor-specific B cells and the Abs that they produce can cause rejection of transplants. Less clear and more controversial, however, is the possibility that donor-specific B cells and the Abs that they produce are one or more means by which transplants can be protected from injury. In this article, we review and discuss this possibility and consider how less well-known functions of B cells and Abs might impact on the design of therapeutics and the management of transplant recipients.
Volume
190
Issue
3
First Page
875
Last Page
879
ISSN
1550-6606
Published In/Presented At
Cascalho, M. I., Chen, B. J., Kain, M., & Platt, J. L. (2013). The paradoxical functions of B cells and antibodies in transplantation. Journal of immunology (Baltimore, Md. : 1950), 190(3), 875–879. https://doi.org/10.4049/jimmunol.1100120
Disciplines
Medicine and Health Sciences
PubMedID
23335803
Department(s)
Department of Surgery
Document Type
Article