Aminoglutethimide medical adrenalectomy for advanced prostatic carcinoma.

Publication/Presentation Date

2-1-1976

Abstract

Complete adrenal suppression with aminoglutethimide has been accomplished in 7 patients with progressive stage D carcinoma of the prostate who had become refractory to orchiectomy and the administration of exogenous estrogens. A favorable response was noted in 3 patients. These preliminary results indicate that this agent may be as useful as surgical adrenalectomy in the treatment of progressive prostatic carcinoma. A brief discussion of the pharmacology of this agent, its mode of administration and the side effects are presented.

Volume

115

Issue

2

First Page

170

Last Page

174

ISSN

0022-5347

Disciplines

Medicine and Health Sciences

PubMedID

765499

Department(s)

Department of Surgery

Document Type

Article

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