Experimental cancer of the bowel in the Nb rat.
Publication/Presentation Date
10-1-1983
Abstract
An animal model of bowel cancer, induced by 1,2-dimethyl hydrazine, has been developed in the Nb rat. Invasive polypoid carcinomas of the colon were noted in nine rats surviving 29 weeks after the carcinogen was first administered. Two of these nine rats also developed duodenal carcinomas. Because dosage schedules are known from previous experiments with the Nb rat, this animal model may be useful for evaluating the effects of cytotoxic drugs on experimental bowel cancer.
Volume
24
Issue
2
First Page
96
Last Page
98
ISSN
0022-4790
Published In/Presented At
Joehl, R. J., & Drago, J. R. (1983). Experimental cancer of the bowel in the Nb rat. Journal of surgical oncology, 24(2), 96–98. https://doi.org/10.1002/jso.2930240205
Disciplines
Medicine and Health Sciences
PubMedID
6632901
Department(s)
Department of Surgery
Document Type
Article
COinS