Chemotesting of prostate cancer in xenografts.
Publication/Presentation Date
7-1-1989
Abstract
The subrenal capsule assay in the Nb rat, a rapid in vivo chemosensitivity assay, was used to evaluate human prostatic adenocarcinoma tissue. Pathologically confirmed prostate adenocarcinoma tissue from six patients, stages B2 to D1, was surgically implanted and grown for 7 days. The rats received chemotherapy on days 1-5. Effects were determined from tumor volume measurements and showed that Adriamycin (doxorubicin) was the most effective agent in three of six of the tumors. Two of the tumors responded to cisplatin and one to methotrexate.
Volume
41
Issue
3
First Page
198
Last Page
200
ISSN
0022-4790
Published In/Presented At
Byard, M. A., Smith, J. J., & Drago, J. R. (1989). Chemotesting of prostate cancer in xenografts. Journal of surgical oncology, 41(3), 198–200. https://doi.org/10.1002/jso.2930410313
Disciplines
Medicine and Health Sciences
PubMedID
2747245
Department(s)
Department of Surgery
Document Type
Article