Comparison of whole versus partial vertebral body stereotactic body radiation therapy for spinal metastases.
Publication/Presentation Date
4-1-2012
Abstract
The purpose of this study is to evaluate the difference in clinical outcomes for patients with metastatic spine disease treated with a whole versus partial vertebral body contouring approach. A retrospective study was performed for the clinical outcomes of 154 metastatic lesions to the spine in 117 patients treated with stereotactic body radiation therapy (SBRT) using the Cyberknife(TM) Robotic Radiosurgery System. Each patient was treated with a single session of radiotherapy using either a whole (WB) or a partial vertebral body contour approach (PB). The primary endpoint was re-treatment rate and the secondary endpoints were pain status, neurologic status, toxicity, tumor control, and survival. The WB group had a lower re-treatment rate (11% (WB) vs. 18.6% (PB), p=0.285). Prior surgery status (β=1.953, OR=7.052, p
Volume
11
Issue
2
First Page
105
Last Page
115
ISSN
1533-0338
Published In/Presented At
Patel, V. B., Wegner, R. E., Heron, D. E., Flickinger, J. C., Gerszten, P., & Burton, S. A. (2012). Comparison of whole versus partial vertebral body stereotactic body radiation therapy for spinal metastases. Technology in cancer research & treatment, 11(2), 105–115. https://doi.org/10.7785/tcrt.2012.500239
Disciplines
Medicine and Health Sciences
PubMedID
22335404
Department(s)
Department of Surgery
Document Type
Article