Alternate Seizure Spread with Agenesis of the Corpus Callosum.
Publication/Presentation Date
6-1-2021
Abstract
Agenesis of the corpus callosum is a brain malformation that can occur in isolation or in conjunction with other congenital or developmental defects. The clinical sequelae of this condition include epilepsy, cognitive deficits, developmental delay, and various neurological and psychiatric disorders. Here we present the case of a patient with congenital complete agenesis of the corpus callosum and medically refractory epilepsy who underwent stereoelectroencephalography. This identified a left frontal ictal focus and revealed that contralateral spread occurred though the anterior commissure, a rare and interesting occurrence. Left frontal resection resulted in significant improvement. This demonstrates the role of the anterior commissure in ictal spread and the potential for novel methods of seizure spread in patients with temporal lobe epilepsy that must be considered in a surgical approach.
Volume
11
Issue
1
First Page
100
Last Page
105
ISSN
2233-6249
Published In/Presented At
Velagapudi, L., Matias, C. M., Ambrose, T. M., Sperling, M. R., Nei, M., Wu, C., & Sharan, A. D. (2021). Alternate Seizure Spread with Agenesis of the Corpus Callosum. Journal of epilepsy research, 11(1), 100–105. https://doi.org/10.14581/jer.21014
Disciplines
Medicine and Health Sciences
PubMedID
34395230
Department(s)
Department of Surgery
Document Type
Article
