Faster Return to Intended Oncologic Treatment (RIOT) After Trisectionectomy Does Not Translate to Better Outcomes.
Publication/Presentation Date
2-1-2021
Abstract
BACKGROUND: Resection with trisectionectomy may necessitate liver molding for adequate future liver remnant (FLR), and subsequent complications can impact return to intended oncologic therapy (RIOT). This study evaluated whether a difference in RIOT exists with the use of molding and between liver molding techniques (associating liver partition and portal vein ligation for staged hepatectomy [ALPPS] and portal vein embolization [PVE]) with trisectionectomy.
METHODS: A retrospective review evaluated trisectionectomies for malignancy. Outcomes were compared with and without molding, and RIOT was determined.
RESULTS: Fifty-one patients underwent trisectionectomy: 11 ALPPS, 14 PVE, 26 without molding. 73% of ALPPS, 64% of PVE, and 58% without molding achieved RIOT (
CONCLUSIONS: Liver molding should not cause apprehension as there are no differences in achieving RIOT. Although technique alters time to RIOT, this does not translate into improved outcomes, implicating disease biology, and regeneration stimulus.
Volume
87
Issue
2
First Page
309
Last Page
315
ISSN
1555-9823
Published In/Presented At
Baimas-George, M., Watson, M., Pickens, R. C., Sulzer, J., Murphy, K. J., Ocuin, L., Baker, E., Martinie, J., Iannitti, D., & Vrochides, D. (2021). Faster Return to Intended Oncologic Treatment (RIOT) After Trisectionectomy Does Not Translate to Better Outcomes. The American surgeon, 87(2), 309–315. https://doi.org/10.1177/0003134820950687
Disciplines
Medicine and Health Sciences
PubMedID
32936007
Department(s)
Department of Surgery, Lehigh Valley Topper Cancer Institute
Document Type
Article