Comparison of pulsatile perfusion and cold storage for paired kidney allografts.

Publication/Presentation Date

10-15-2008

Abstract

Use of pulsatile perfusion to optimize outcomes in deceased donor kidney transplantation remains controversial. This study is a retrospective analysis of all cadaveric renal allografts procured locally by our center over a 3-year period. Kidney pairs were identified in which one kidney underwent pulsatile perfusion and transplantation at our center, whereas the contra-lateral kidney underwent cold storage and transplantation at another center. Eighty-eight percent of the exported kidneys were six-antigen matches. Study outcomes included 1-year graft and patient survival, delayed graft function, and need for posttransplant dialysis. Recipients had similar demographic and disease characteristics. Survival for pulsatile perfusion and cold storage were 95% and 88% (graft, P=0.43) and 98% and 90% (patient, P=0.36), respectively. The incidence of delayed graft function was 5% and 35% (P< 0.01), whereas posttransplant dialysis was 5% and 30% (P< 0.01), for pulsatile perfusion and cold storage, respectively. These data support routine use of pulsatile perfusion.

Volume

86

Issue

7

First Page

1006

Last Page

1009

ISSN

1534-6080

Disciplines

Medicine and Health Sciences

PubMedID

18852670

Department(s)

Department of Surgery

Document Type

Article

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