Predicting Long Term Outcome in Patients Treated With Continuous Flow Left Ventricular Assist Device: The Penn-Columbia Risk Score.
Publication/Presentation Date
3-7-2018
Abstract
BACKGROUND: Predicting which patients are unlikely to benefit from continuous flow left ventricular assist device (LVAD) treatment is crucial for the identification of appropriate patients. Previously developed scoring systems are limited to past eras of device or restricted to specific devices. Our objective was to create a risk model for patients treated with continuous flow LVAD based on the preimplant variables.
METHODS AND RESULTS: We performed a retrospective analysis of all patients implanted with a continuous flow LVAD between 2006 and 2014 at the University of Pennsylvania and included a total of 210 patients (male 78%; mean age, 56±15; mean follow-up, 465±486 days). From all plausible preoperative covariates, we performed univariate Cox regression analysis for covariates affecting the odds of 1-year survival following implantation (
CONCLUSION: We present a novel risk score and its validation for prediction of long-term survival in patients with current types of continuous flow LVAD support.
Volume
7
Issue
6
ISSN
2047-9980
Published In/Presented At
Birati, E. Y., Hanff, T. C., Maldonado, D., Grandin, E. W., Kennel, P. J., Mazurek, J. A., Vorovich, E., Seigerman, M., Howard, J. L. L., Acker, M. A., Naka, Y., Wald, J., Goldberg, L. R., Jessup, M., Atluri, P., Margulies, K. B., Schulze, P. C., & Rame, J. E. (2018). Predicting Long Term Outcome in Patients Treated With Continuous Flow Left Ventricular Assist Device: The Penn-Columbia Risk Score. Journal of the American Heart Association, 7(6), e006408. https://doi.org/10.1161/JAHA.117.006408
Disciplines
Medicine and Health Sciences
PubMedID
29514805
Department(s)
Department of Surgery
Document Type
Article