Bridging to Heart Transplantation With Intraaortic Balloon Pump Versus Impella 5.5.
Publication/Presentation Date
4-2-2025
Abstract
In this study, we compare the clinical characteristics and courses of patients directly bridged to heart transplant with intraaortic balloon pump (IABP) versus Impella 5.5. We performed a retrospective cohort study of single-center institutional data including all adult patients at our institution bridged to transplant with either IABP or Impella 5.5 support between October 18, 2018, and May 31, 2023. Ninety-one heart transplant recipients were included in this study, of whom 54 (59%) were bridged on IABP and 37 (41%) were bridged on Impella 5.5. Patients supported with Impella 5.5 had comparable baseline characteristics compared to those bridged on IABP (all p > 0.05). However, Impella 5.5 patients had lower vasoactive inotropic scores during their temporary mechanical circulatory support (MCS) period than those bridged on IABP (all p < 0.05). Duration of MCS and post-transplant intensive care unit (ICU) length of stay were longer for Impella 5.5 patients (all p < 0.05), but rates of complications after transplant were comparable (all p > 0.05). Survival at 1 year post-transplant was significantly greater for the Impella 5.5 group (100% vs. 87%; p = 0.039). Given the increased use of MCS as a bridge to transplant, this project has important implications for preoperative management of waitlist patients.
ISSN
1538-943X
Published In/Presented At
Kim, S. E., Shin, M., Iyengar, A., Weingarten, N., Jin, D., Wilson, R., Asher, M., Toubat, O., & Atluri, P. (2025). Bridging to Heart Transplantation With Intraaortic Balloon Pump Versus Impella 5.5. ASAIO journal (American Society for Artificial Internal Organs : 1992), 10.1097/MAT.0000000000002432. Advance online publication. https://doi.org/10.1097/MAT.0000000000002432
Disciplines
Medicine and Health Sciences
PubMedID
40171958
Department(s)
Department of Surgery
Document Type
Article