Management of Nonfunctioning Recurrent Pituitary Adenomas.

Authors

Christopher J Farrell
Tomas Garzon-Muvdi
Judd H Fastenberg
Gurston G Nyquist
Mindy R Rabinowitz
Marc R Rosen
James J Evans

Publication/Presentation Date

10-1-2019

Abstract

Pituitary adenomas are typically slow-growing benign tumors. However, 50% to 60% of tumors progress following subtotal resection and up to 30% recur after apparent complete resection. Options for treatment of recurrent pituitary adenomas include repeat surgical resection, radiation therapy, and systemic therapies. There is no consensus approach for the management of recurrent pituitary adenomas. This article reviews the natural history of recurrent adenomas and emerging biomarkers predictive of clinical behavior as well as the outcomes associated with the various treatment modalities for these challenging tumors, with an emphasis on the surgical treatment.

Volume

30

Issue

4

First Page

473

Last Page

482

ISSN

1558-1349

Published In/Presented At

Farrell, C. J., Garzon-Muvdi, T., Fastenberg, J. H., Nyquist, G. G., Rabinowitz, M. R., Rosen, M. R., & Evans, J. J. (2019). Management of Nonfunctioning Recurrent Pituitary Adenomas. Neurosurgery clinics of North America, 30(4), 473–482. https://doi.org/10.1016/j.nec.2019.05.006

Disciplines

Medicine and Health Sciences

PubMedID

31471054

Department(s)

Department of Surgery

Document Type

Article