Complications of transradial versus transfemoral access for neuroendovascular procedures: a meta-analysis.

Publication/Presentation Date

8-1-2022

Abstract

BACKGROUND: Transradial access (TRA) has gained increased usage among neurointerventionalists. However, the overall safety profile of access site complications (ASCs) and non-access site complications (NASCs) of TRA versus transfemoral access (TFA) for neuroendovascular procedures remains unclear.

METHODS: A systematic literature review and meta-analysis using a random effects model was conducted to investigate the pooled odds ratios (OR) of ASCs and NASCs. Randomized, case-control, and cohort studies comparing access-related complications were analyzed. An assessment of study heterogeneity and publication bias was also completed.

RESULTS: Seventeen comparative studies met the inclusion criteria for final analysis. Overall, there was a composite ASC rate of 1.8% (49/2767) versus 3.2% (168/5222) for TRA and TFA, respectively (P< 0.001). TRA was associated with a lower odds of ASC compared with TFA (OR 0.42; 95% CI 0.25 to 0.68, P< 0.001, I

CONCLUSION: On meta-analysis, the current literature indicates that TRA is associated with a lower incidence of ASCs compared with TFA, but is not associated with a lower rate of NASCs.

Volume

14

Issue

8

First Page

820

Last Page

825

ISSN

1759-8486

Disciplines

Medicine and Health Sciences

PubMedID

34479985

Department(s)

Department of Surgery

Document Type

Article

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