Late pandemic COVID-19 positivity at the time of thrombectomy is associated with poor outcomes and tandem carotid pathology.
Publication/Presentation Date
1-1-2025
Abstract
OBJECTIVES: COVID-19 is an independent risk factor for ischemic stroke. Studies from early in the pandemic show increased rates of unfavorable recanalization, poor outcomes, and mortality in patients who were COVID-19 positive at the time of mechanical thrombectomy. However, there are currently no studies examining these parameters during the later pandemic when circulating variants were less virulent.
MATERIALS AND METHODS: We performed a retrospective review of mechanical thrombectomies from 12/2020 to 3/2023. Patients who were COVID-19 positive at the time of thrombectomy were included. Demographic, procedural, and 90-day functional outcomes were evaluated.
RESULTS: Of 306 patients undergoing mechanical thrombectomy for acute ischemic stroke between 12/2020 and 3/2023, 18 were COVID-19 positive. Compared with the COVID-19 negative cohort, there were lower rates of favorable recanalization (73% vs. 92%,
CONCLUSION: Late in the pandemic, outcomes remained comparable to those observed in the early pandemic for patients positive for COVID-19 at the time of mechanical thrombectomy. This case series also demonstrates increased tandem carotid pathology in the COVID-19 cohort. While COVID-19 may not influence outcome to the degree that age and NIHSS do, the excess mortality continues to suggest a negative effect despite lower virulence.
Volume
16
First Page
1513124
Last Page
1513124
ISSN
1664-2295
Published In/Presented At
Thompson, L. J. R., Houk, C., Ellens, N. R., Kohli, G. S., Schartz, D., Proper, D., Bhalla, T., Bender, M. T., & Mattingly, T. K. (2025). Late pandemic COVID-19 positivity at the time of thrombectomy is associated with poor outcomes and tandem carotid pathology. Frontiers in neurology, 16, 1513124. https://doi.org/10.3389/fneur.2025.1513124
Disciplines
Medicine and Health Sciences
PubMedID
40066309
Department(s)
Department of Surgery
Document Type
Article